Renal Nerve Ablation for Resistant Hypertension

Renal nerve ablation for resistant hypertension.

[Renal-nerve ablation in patients with resistant hypertension: caution is still needed].

The autonomic nervous system plays a major role in blood pressure regulation and pathogenesis of essential hypertension. Before the advent of orally active antihypertensive treatments, surgical sympathectomy was the only therapeutic option in severely hypertensive patients. It was effective in reducing blood pressure in half of these patients. However, this intervention was associated with high...

Renal Denervation by Ablation with Innovative Technique in Resistant Hypertension

DOI: 10.5935/abc.20130194 Introduction Hypertension is the cause of thousands of deaths annually1, and half of the patients treated present controlled blood pressure (BP)2. Resistant hypertension (RH)is defined when the BP remains above the recommended targets with the use of three antihypertensive drugs with synergistic actions at maximum doses recommended and tolerated, preferably one being a...

Renal denervation for resistant hypertension?

Ever since Schlaich et al.1 first reported on a patient with a blood pressure of 161/107 mm Hg (despite treatment with seven different antihypertensive drugs) that decreased to 127/81 mm Hg after renal denervation, the medical community has been enamored with this procedure. Resistant hypertension evolved into a fashionable diagnosis, and the number of publications pertaining to it grew rapidly...

Renal denervation for resistant hypertension.

There is a marked contrast between the high prevalence of hypertension and the low rates of adequate control. A subset of patients with suboptimal blood pressure control have drug-resistant hypertension, in the pathophysiology of which chronic sympathetic hyperactivation is significantly involved. Sympathetic renal denervation has recently emerged as a device-based treatment for resistant hyper...